Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Thalassemia Research Center, Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand. Molecular Medicine Graduate Program, Multidisciplinary Unit, Faculty of Science, Mahidol University, Bangkok, Thailand. Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand. Department of Pharmacology, Faculty of Dentistry, Mahidol University, Bangkok, Thailand. Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand. Electronic address: nathawut.sib@mahidol.ac.th.